RAD 150 vs RAD 140 SARM?
There is an ongoing debate over which Selective Androgen Receptor Modulator (SARM) is better at gaining lean muscle.
The SARMs are similar in many regards yet also have a few stark differences.
Interested? Learn more about the 6 primary things that make RAD 150 different from RAD 140 SARM, below:
RAD 150 vs RAD 140: 6 Differences
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RAD 150 (TLB-150 Benzoate) was recently introduced as a new and improved version of Testolone (RAD 140).
However, comparing the 2 muscle growth supplements is a bit unfair since they rival each other in many respects.
In fact, RAD 150 and RAD 140 are frequently combined in a weight stack for maximum results (more details, below).
RAD 140 and RAD 150 function as Selective Androgen Receptor Modulators (SARMs).1
Selective Androgen Receptor Modulators are popular with bodybuilders because they improve many aspects of physical performance.
SARMs promote weight loss and stimulate new muscle growth.2
As a result, these compounds are known to provide many of the same benefits as steroids but without the harmful side effects.
Nevertheless, SARMs like RAD 140 and RAD 150 are still being researched.3 4
For this reason, more is still being discovered about the SARMs, including how they may support each other in building lean muscle.
Be that as it may, clinical studies have already discovered 6 key differences that make RAD 150 different from RAD 140:
● Purpose
● Mechanism of Action
● Bioavailability (Half-Life)
● Benefits of SARM
● Dosage / Cycle
● Side Effects / Health Risks
RAD 150 and RAD 140 offer a complete body makeover.
The SARMs stimulate rapid new growth among other benefits designed to make you feel better and younger.5
Still, users must understand that neither substance is currently regulated by the FDA.
Consequently, the aspects that make the SARMs different is largely based on word-of-mouth reputation and limited clinical studies.6
RAD 150 vs RAD 140?
Discover 5 things that make the 2 SARMs different from each other, below:
#1. Purpose
Click Here Now to pick up RAD 140 and / or RAD 150 from our top rated source.
Testolone (RAD 140) and TLB-150 Benzoate (RAD 150) were developed for the same reason.
The Selective Androgen Receptor Modulators (SARMs) are designed to produce weight loss and stimulate muscle growth.7
For this reason, most SARM users burn excess fat and replace it with lean muscle.
However, RAD 150 is different from RAD 140 because it's esterified (more information below).
RAD 150 features improved bioavailability and functioning within the body.
In other words, the SARM produces faster, more impressive results.
Previously, RAD 140 had gained notoriety as a means for gaining lean muscle and increasing muscle mass.8
Notwithstanding, the short half-life (more details, below) made it difficult for the SARM to maintain a long-term influence.
Thus, some argue that RAD 150 is a better, improved version of RAD 140.
What is known is that both SARMs promote muscle growth and avoid the dangerous side effects of anabolic steroids.
Thus, individuals can get bigger, stronger, and more ripped without compromising personal health.
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#2. Mechanism of Action
RAD 150 SARM functions much like RAD 140, but has undergone the process of esterification.
Esterification is a chemical process designed to stabilize and improve the proportion of the drug utilized in the body.
Thus, RAD 150 seeks to improve the half-life, or the amount of time the effects from the compound remain in the bloodstream.
RAD 150, like RAD 140, is designed to bind to androgen receptors (muscle tissue) selectively.9
Consequently, the SARM avoids binding to other receptors and, therefore, disrupting other biological / hormonal activities.
For this reason, most agree that SARMs like RAD 140 and RAD 150 are safer alternatives to anabolic steroids.
Be that as it may, researchers are still learning more about the compounds.
Therefore, until more clinical studies are published, quality information is not widespread.
Still, most acknowledge that RAD 150 and RAD 140 are loaded with potential.
And, since the SARMs complement each other in many regards, function great together in a weight stack.
#3. Bioavailability (Half-Life)
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RAD 150 vs RAD 140?
The biggest difference between the 2 SARMs is the bioavailability, or half-life.
When RAD 140 was first introduced, it was popular with bodybuilders due to the increased energy, muscle mass, and improved sexual performance.
However, the short half-life of the compound made it difficult to produce results over an extended period.
Thus, RAD 150 was created with the intention of delivering longer, more sustainable results.
RAD 150 features a long half-life that is reported to last anywhere from 24 - 48 hours.
On the other hand, the RAD 140 SARM only has a half-life of 1 - 2 hours.
Consequently, it's hard to achieve long-term results using the SARM by itself.
Be that as it may, many individuals combine RAD 140 with other peptides and SARMs for quicker, better results.
#4. Benefits of SARM
RAD 150 vs RAD 140?
Another subject that is frequently discussed in the debate between the SARMs is the reported health benefits.
Both RAD 150 and RAD 140 are tremendous supplements for gaining lean muscle and increasing muscle mass.
However, users must beware of the very short half-life of RAD 140.
Moreover, RAD 150 and RAD 140 are not exactly the same compounds.
The SARMs increase muscle definition and strength with substantial gains reported in many users.
Additionally, RAD 150 improves metabolism and manages appetite, critical components to weight loss.
Meanwhile, RAD 140 is a better choice for those seeking to heal faster from serious injuries.
RAD 140 also promotes quick recovery post-workout for individuals seeking to bounce back from a grueling workout.
There is limited evidence (more details, below) that RAD 150 and RAD 140 support older folks looking to reverse the signs of aging.
RAD 140 does feature promise for treating osteoporosis and other muscle-wasting diseases.
Still, more research is necessary to make a final determination.
RAD 140 and RAD 150 are frequently compared to other SARMs, like Ostarine (MK-2866) and Ligandrol (LGD-4033), to stack on new lean muscle.
Furthermore, both SARMs function great with Andarine (S-4), Cardarine (GW-501516), and Ibutamoren (MK-677).
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#5. Dosage / Cycle
What is the recommended dosage for RAD 140 and RAD 150?
Unfortunately, new users often have trouble finding access to quality, reliable information.
Furthermore, it doesn't help that most SARMs are not currently approved or regulated by the FDA.
Therefore, most new users are left in the dark and must determine what is best for their needs.
Be that as it may, you'll discover that many previous users have shared their experiences online.
These personal reviews contain helpful information regarding safe and responsible use.
Previous users generally report that a safe dosage for Testolone (RAD 140) is between 5mg and 20mg per day.
Often, beginners use lower doses (5mg - 10mg) for the first cycle (6 - 8 weeks) before advancing to a higher dose (10mg - 30mg).
Regardless, a cycle should never exceed a period of longer than 2 months before taking a break from the SARM.
RAD 150, on the other hand, is more potent and has longer-lasting effects than RAD 140.
Accordingly, users are suggested to administer between 5mg - 10mg per day within an 8-week cycle.
Generally, users cycle off both RAD 150 and RAD 140 with Post-Cycle Therapy (PCT).
Post-Cycle Therapy (PCT) products are for sale online and enable the body to recover after introducing the body to a new supplement.
#6. Side Effects / Health Risks
In general, people who use RAD 140 and RAD 150 do not report any serious side effects or health risks.
Despite this, new users should always consult a physician before administering a new compound.
SARMs are generally well tolerated yet may interfere with other medications or preexisting health conditions.
In the past, most users had a positive experience using SARMs like RAD 140 and RAD 150.
Nevertheless, there are always potential risks with any new substance that is not fully understood.
RAD 140 and RAD 150 are recent creations that have not been extensively studied.
Consequently, it's difficult to get access to reliable information and quality research.
Notwithstanding, the initial discoveries suggest that both SARMs are complete game-changers.
Regardless, new users should consider the following risks of using RAD 140 and RAD 150:
● Fatigue
● Hair Loss
● Mood Changes
● Trouble Sleeping
● Liver Problems 10
Selective Androgen Receptor Modulators (SARMs) do produce spikes in energy and endurance that may keep you up at night.
In addition, RAD140 was shown in a limited clinical study to negatively impact skeletal muscle adaptation and increased mortality risk in rats.11
Often, it takes a couple of weeks to adjust to the compound.
Accordingly, most symptoms are the most pronounced during the initial weeks of the cycle.
Despite this, make sure to stop using the compound if the symptoms persist and meet with a physician.
Generally, users follow up with blood work following a cycle to determine if the SARM impacted any hormones.
Previously, some users have noticed a decrease in testosterone, making this step critical.
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RAD 150 vs RAD 140: Frequently Asked Questions
Which SARM is better at losing weight and gaining lean muscle?
You'll find some that prefer the benefits of RAD 140 because of the quick healing and recovery.
Meanwhile, others will argue that RAD 150 is the better SARM because of the long half-life.
Discover more answers to frequently asked questions, below:
Is RAD 140 or RAD 150 the better SARM?
The jury is divided.
For some, Testolone (RAD 140) has not let them down in the past.
Therefore, they have trouble dismissing the many benefits of the SARM.
However, RAD 150 generally produces faster results due to the much longer half-life.
Regardless, both SARMs are usually combined in the same weight stack for maximum results.
What is the half-life of RAD 140?
The biggest problem with Testolone (RAD 140) is the short half-life.
In general, RAD 140's effects last in the bloodstream for an estimated 1 - 2 hours.
It's a huge contrast from RAD 150, which can exist in the bloodstream for days.
Thus, RAD 140 functions best combined with other peptides and SARMs in a weight stack.
What is the half-life of RAD 150?
RAD 150 features a very long half-life.
In fact, most estimate that the half-life of the SARM is somewhere between 24 - 48 hours.
Unfortunately, there is a lack of precise data, leaving the half-life open to interpretation.
Regardless, previous users acknowledge the effects are much longer lasting and permanent.
Can I use both SARMs?
Yes, great question.
RAD 140 and RAD 150 work better together than alone.
At first, RAD 140 was introduced as a muscle growth supplement.
However, the limited bioavailability made it difficult for the SARM to produce sustainable, long-term results.
Thus, RAD 150 was created and immediately started an unfair competition.
In reality, both SARMs support each other more than they do things differently.
Regardless, it's important for new users to compare and contrast the SARMs.
Are SARMs legit for muscle growth?
Yes, the evidence is clear.
Selective Androgen Receptor Modulators (SARMs) rapidly burn fat and replace it with lean muscle.
These compounds bind to androgen receptors selectively.
Consequently, SARMs avoid disrupting other hormones and natural processes, unlike steroids.
In the past, results have been based on men and women who have posted about their experiences online.
Thus, caution is advised since most of these compounds are not currently regulated by the U.S. Food & Drug Administration (FDA).
New users should always consult with a trusted physician before using any new supplement.
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RAD 150 vs RAD 140 SARM Summary
RAD 150 vs RAD 140?
The debate over the best SARM for getting stronger and more ripped remains open to discussion.
RAD 140 was initially designed as a safer and more effective alternative to steroids and other performance-enhancing drugs.
Meanwhile, RAD 150 was created to improve the effects and long-term results of RAD 140.
Thus, some argue that RAD 150 is a newer, better, more improved version of RAD 140.
However, the debate continues as research and clinical trials remain ongoing.
RAD 140 and RAD 150 function great together in a weight stack designed to increase lean muscle and muscle mass.
Click Here Now to pick up RAD 140 and / or RAD 150 from our top rated source.
References
1. Solomon ZJ, Mirabal JR, Mazur DJ, Kohn TP, Lipshultz LI, Pastuszak AW. Selective Androgen Receptor Modulators: Current Knowledge and Clinical Applications. Sex Med Rev. 2019 Jan;7(1):84-94. doi: 10.1016/j.sxmr.2018.09.006. Epub 2018 Nov 30. PMID: 30503797; PMCID: PMC6326857.
2. Christiansen AR, Lipshultz LI, Hotaling JM, Pastuszak AW. Selective androgen receptor modulators: the future of androgen therapy? Transl Androl Urol. 2020 Mar;9(Suppl 2):S135-S148. doi: 10.21037/tau.2019.11.02. PMID: 32257854; PMCID: PMC7108998.
3. National Center for Biotechnology Information. PubChem Compound Summary for CID 44200882, Testolone.
4. National Center for Biotechnology Information. PubChem Compound Summary for CID 32771, 2-[5-chloropentyl(methyl)amino]-N-(2,6-dimethylphenyl)acetamide.
5. Bhasin S. Selective Androgen Receptor Modulators as Function Promoting Therapies. J Frailty Aging. 2015;4(3):121-2. doi: 10.14283/jfa.2015.65. PMID: 27030938; PMCID: PMC6039107.
6. Wagener F, Euler L, Görgens C, Guddat S, Thevis M. Human In Vivo Metabolism and Elimination Behavior of Micro-Dosed Selective Androgen Receptor Modulator RAD140 for Doping Control Purposes. Metabolites. 2022 Jul 20;12(7):666. doi: 10.3390/metabo12070666. PMID: 35888790; PMCID: PMC9325264.
7. Miller CP, Shomali M, Lyttle CR, O'Dea LS, Herendeen H, Gallacher K, Paquin D, Compton DR, Sahoo B, Kerrigan SA, Burge MS, Nickels M, Green JL, Katzenellenbogen JA, Tchesnokov A, Hattersley G. Design, Synthesis, and Preclinical Characterization of the Selective Androgen Receptor Modulator (SARM) RAD140. ACS Med Chem Lett. 2010 Dec 2;2(2):124-9. doi: 10.1021/ml1002508. PMID: 24900290; PMCID: PMC4018048.
8. Jayaraman A, Christensen A, Moser VA, Vest RS, Miller CP, Hattersley G, Pike CJ. Selective androgen receptor modulator RAD140 is neuroprotective in cultured neurons and kainate-lesioned male rats. Endocrinology. 2014 Apr;155(4):1398-406. doi: 10.1210/en.2013-1725. Epub 2014 Jan 15. PMID: 24428527; PMCID: PMC3959610.
9. LoRusso P, Hamilton E, Ma C, Vidula N, Bagley RG, Troy S, Annett M, Yu Z, Conlan MG, Weise A. A First-in-Human Phase 1 Study of a Novel Selective Androgen Receptor Modulator (SARM), RAD140, in ER+/HER2- Metastatic Breast Cancer. Clin Breast Cancer. 2022 Jan;22(1):67-77. doi: 10.1016/j.clbc.2021.08.003. Epub 2021 Aug 20. PMID: 34565686.
10. Leung K, Yaramada P, Goyal P, Cai CX, Thung I, Hammami MB. RAD-140 Drug-Induced Liver Injury. Ochsner J. 2022 Winter;22(4):361-365. doi: 10.31486/toj.22.0005. PMID: 36561105; PMCID: PMC9753945.
11. Brown AM, Ganjayi MS, Baumann CW. RAD140 (Testolone) negatively impacts skeletal muscle adaptation, frailty status and mortality risk in female mice. Clin Exp Pharmacol Physiol. 2023 Dec;50(12):973-983. doi: 10.1111/1440-1681.13824. Epub 2023 Sep 27. PMID: 37758180.
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