Protein C deficiency is a rare genetic trait characterised by an increased tendency to form blood clots. Protein C is a vitamin-K-dependent anticoagulant protein manufactured in the liver and circulated in the plasma.
Protein C deficiency is a prethrombotic (a thrombus is a clot) disorder which may be a result of congenital biochemical defects or associated with other thrombotic disorders.
Clots in the leg veins may cause symptoms such as pain, tenderness, swelling, discolouration and ulceration of the skin depending on the site of the clots.
