Fat Cells Retain 'Obesity Memory': Study
Image: Unsplash
22 Nov 2024
Researchers from ETH Zurich discovered fat cells retain an epigenetic memory of obesity after weight loss
Image: Unsplash
This memory, termed "obesogenic memory," makes previously obese mice regain weight faster on high-fat diets
Image: Pexels
Obesogenic memory involves epigenetic changes that affect gene activity, influencing weight rebound tendencies in individuals
Image: Pexels
Genes linked to inflammation are more active, while fat cell identity genes show reduced activity
Image: Pexels
Similar epigenetic signatures were observed in humans who had weight loss surgeries, limiting full causal analysis
Image: Pexels
This phenomenon explains the "yo-yo" effect of weight gain after successful dieting or medication
Image: Pexels
Researchers suggest targeting these epigenetic changes could improve long-term weight loss and health outcomes
Image: Pexels
Obesity remains a global health crisis, associated with millions of deaths annually, mostly from heart disease
Image: Pexels
Factors like microbiomes, medications, genetics, and now epigenetics contribute to difficulties in maintaining weight loss
Image: Pexels
Until solutions emerge, focusing on healthy eating instead of weight alone may yield better health outcomes
Image: Pexels
Check More Stories
Image: Reuters
Image: Unsplash
Image: Unsplash
ndtv.com