New Blood Test Detects Brain Cancer In One Hour

Image: University Of Notre Dam

31 Aug 2024

A new blood test can detect glioblastoma brain cancer within an hour, using only 100 microliters


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This liquid biopsy surpasses existing tests with excellent accuracy, using biomarkers associated with glioblastoma


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Developed by a US-Australian team, the test is an important step forward in diagnosis


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The method detects epidermal growth factor receptors (EGFRs) found in extracellular vesicles from cancerous cells


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A biochip, costing less than US$2, uses antibodies to detect EGFRs, triggering a voltage change


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In experiments, the test accurately detected cancer biomarkers in blood samples from glioblastoma patients


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The sensor's low noise and high sensitivity make it superior for disease detection


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The biochip detected exosome concentrations as low as 0.01 percent, indicating high replicability


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The test isn't yet specific to glioblastoma, as EGFR mutations are found in other cancers


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Researchers need larger patient cohorts to develop a more specific and comprehensive diagnostic test


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