Scientists May Have Solved Key Weight Loss Mystery
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2o Nov 2024
A new study explores why weight loss often leads to regaining body fat later
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Fat tissue retains a "memory" that may explain why weight loss is hard to maintain
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Dr Ferdinand von Meyenn and his team studied fat cells to understand this phenomenon
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They found transcriptional changes in fat cells of individuals before and after weight reduction
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The study revealed that genes in obese individuals remained deregulated even after weight loss
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Adipose tissue seems "programmed" to regain weight after fat loss, making it harder to maintain
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Von Meyenn suggests weight fluctuations have underlying molecular mechanisms, not just individual willpower
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He hopes the research will help reduce stigma around people struggling with weight management
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Preventative measures, like early intervention, are crucial for combating global obesity trends, von Meyenn stated
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Dr von Meyenn works at ETH Zurich's Laboratory of Nutrition and Metabolic Epigenetics
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