Chilmark, Massachusets:
Hurricane Irene began lashing the US East Coast with rain on Friday ahead of a weekend of violent weather that was almost certain to heap punishment on a vast stretch of shoreline from the Carolinas to Massachusetts.
For hundreds of miles, people in the storm's path headed inland, made last-minute preparations and monitored the hurricane's every subtle movement. Irene had the potential to cause billions of dollars in damage all along a densely populated arc that included Washington, Baltimore, Philadelphia, New York, Boston and beyond. At least 65 million people could be affected.
US President Barack Obama said all indications point to the storm being a historic hurricane.
"I cannot stress this highly enough. If you are in the projected path of this hurricane, you have to take precautions now," Mr Obama said on Friday from Martha's Vineyard, where he was wrapping up a vacation.
The President was to return to the White House on Saturday, the same day the storm is expected to pass through the area around the nation's capital.
As Irene trudged northwest from the Bahamas, rain from its outer bands began falling along the North and South Carolina coast. Swells and 6- to 9-foot waves were reported along the Outer Banks. Winds were expected to pick up later. Thousands had already lost power as the fringes of the storm began raking the shore.
Hurricane warnings remained in effect from North Carolina to New Jersey. Hurricane watches were in effect even farther north and included Long Island, Martha's Vineyard and Nantucket, Mass.
Risks from Irene's wrath were many: surging seas, drenching rains, flash floods and high winds. The head of the Federal Emergency Management Agency had warned previously that this is one of the largest populations to be affected by one storm at one time.
On Friday morning, FEMA Director Craig Fugate and Homeland Security Secretary Janet Napolitano pleaded with people to heed warnings.
"Evacuation orders are key," Fugate said. "People need to leave early, travel a safe distance and get somewhere safe. All the preparation and planning will be in vain if people don't heed those evacuation orders."
In addition to widespread wind and water damage, Irene could also push crude oil prices higher if it disrupts refineries in Delaware, New Jersey, Pennsylvania and Virginia, which produce nearly 8 percent of US gasoline and diesel fuel.
By late Friday morning, Irene remained a Category 2 storm with maximum sustained winds near 105 mph (169 kph). Little change in strength was expected by the time Irene reaches the North Carolina coast on Saturday, but forecasters at the National Hurricane Center warned it would be a large and dangerous storm nonetheless.
In North Carolina, traffic was steady on Friday as people fled the Outer Banks and beach towns. A day earlier, tourists were ordered to leave the barrier islands, and many residents also heeded authorities' admonitions to get out.
At a gas station in Nags Head, Pete Reynolds wanted to make sure he had enough fuel for the long trip. The retired teacher spent part of Thursday getting his house ready for the hurricane. He and his wife then headed to New Jersey to stay with their son's family.
"We felt like we would be OK, and we could ride out the storm," Reynolds said. "But when they announced mandatory evacuations, I knew it was serious."
North Carolina Governer Beverly Perdue said state troopers, the Red Cross and the National Guard were in place to deal with the storm's aftermath. But she warned coastal residents not to risk waiting out the storm and hoping for help after it passed.
"You can't count on that. Folks need to decide that they need to get out now," she said.
Later in the day, Perdue said some 3.5 million people in the state could be affected.
North Carolina was just first in line along the Eastern Seaboard - home to some of the nation's priciest real estate.
Besides major cities, sprawling suburbs, ports, airports, highways, cropland and mile after mile of built-up beachfront neighborhoods are in harm's way. In several spots along the coast, hospitals and nursing homes worked to move patients and residents to safety.
"One of my greatest nightmares was having a major hurricane go up the whole Northeast coast," Max Mayfield, the National Hurricane Center's retired director, told The Associated Press on Thursday.
The hurricane could be the strongest to strike the East Coast in seven years, and people were already getting out of the way. Irene already had pummeled the Caribbean, causing floods and power outages.
The center of the storm was still about 330 miles (531 kilometers) south-southwest of Cape Hatteras, N.C., and moving to the north at 14 mph (22 kph).
The latest forecasts showed Irene crashing into the North Carolina coastline on Saturday, then churning up the Eastern Seaboard and drenching areas from Virginia to New York City before a weakened storm reaches New England.
In Washington, Irene dashed hopes of dedicating a 30-foot sculpture to Martin Luther King Jr. on Sunday on the National Mall. While a direct strike on the nation's capital appeared slim, organizers said the forecasts of wind and heavy rain made it too dangerous to summon a throng they expected to number up to 250,000.
Hundreds of thousands of New Yorkers were told on Thursday to pack a bag and be prepared to move elsewhere. The nation's biggest city has not seen a hurricane in decades, and a hurricane warning hasn't been issued there since Hurricane Gloria hit in 1985 as a Category 2 storm, said Ashley Sears, a meteorologist with the National Weather Service.
Even if the winds aren't strong enough to damage buildings in a metropolis made largely of brick, concrete and steel, a lot of New York's subways and other infrastructure are underground, making them subject to flooding.
New York's two airports are close to the water and could be inundated, as could densely packed neighborhoods, if the storm pushes ocean water into the city's waterways, officials said. In 2008, the city had a brush with Tropical Storm Hanna, which dumped 3 inches of rain on Manhattan.
In the last 200 years, New York has seen only a few significant hurricanes. In September 1821, a hurricane raised tides by 13 feet in an hour and flooded all of Manhattan south of Canal Street, the southernmost tip of the city. The area now includes Wall Street and the World Trade Center memorial.
An infamous 1938 storm dubbed the Long Island Express came ashore about 75 miles east of the city and then hit New England, killing 700 people and leaving 63,000 homeless.
New England is also unaccustomed to direct hits from hurricanes.
Maine lobsterman Greg Griffin, who fishes from Portland, still recalls the clobbering from Hurricane Gloria in 1985 and said Irene is not one to ignore.
"We have a young generation of lobstermen who've never experienced a full-blown hurricane," Griffin warned.
The first US injuries from Irene appeared to be in South Florida near West Palm Beach, where eight people were washed off a jetty on Thursday by a large wave churned up by the storm.
Across the Northeast, Irene threatened to flood many miles of land that are already saturated from heavy rain.
Parts of Rhode Island are still recovering from devastating 2010 spring floods. And Connecticut Governer Daniel P. Malloy warned there could be prolonged power outages if Irene dumps up to a foot of additional rain.
The urban population explosion in recent decades also worries New Jersey officials. Governer Chris Christie encouraged anyone on that state's heavily developed shoreline to prepare to leave. One of the popular casinos in Atlantic City had already closed on Friday, and several others planned to shut down later in the day.
The beach community of Ocean City, Md., was taking no chances, ordering thousands of people to leave.
"This is not a time to get out the camera and sit on the beach and take pictures of the waves," said Maryland Governer Martin O'Malley.