Beijing: Police shot dead one suspect and captured another, the statement said.
No further details were provided, and Guangzhou police did not respond to calls from AFP.
Domestic reports said one of the suspects cut a policeman's right hand.
A lone attacker was shot and detained after a slashing attack that wounded six people at the same station last May.
Authorities blamed separatists from the restive mainly Muslim region of Xinjiang for the attack last March in Kunming, the capital of the southwestern province of Yunnan.
Hundreds of people died in Xinjiang last year, most of them members of the Uighur minority according to rights groups.
On Thursday in Beijing China opened the annual session of the National People's Congress, the legislature which is subordinate to the Communist Party.
A man was shot dead by police and another detained after a knife attack at a Chinese train station which left nine people wounded on Friday, police said.
The incident at the main station in Guangzhou happened as China's communist-controlled parliament meets in Beijing and just over a year after a mass stabbing at a railway station in Kunming, when 31 people were killed and four attackers died.
"Someone with a knife slashed a crowd at Guangzhou train station," the southern city's municipal public security bureau said on its verified account on Sina Weibo, China's version of Twitter.
No further details were provided, and Guangzhou police did not respond to calls from AFP.
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A lone attacker was shot and detained after a slashing attack that wounded six people at the same station last May.
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Hundreds of people died in Xinjiang last year, most of them members of the Uighur minority according to rights groups.
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